The first “live” interstellar colonists to arrive successfully on an exoplanet in a nearby system were a group of six malnourished Vietnamese women. (A seventh died in hibernation, as had been statistically predicted.)
Between Sol’s planets, economies of scale and orbital infrastructure allow minor differences in weight to be tolerable. Tickets are still based on mass, as-measured by the travel agency on launch day to the nearest gram, so women and children are cheap. But even if you’re obese, you can still pay your way.
But when you’re talking about interstellar distances, every extra gram you accelerate to and back again requires energy comparable to the annihilation of a weapons-grade quantity of antimatter. That energy has to come from somewhere.
So, because men’s contribution can be saved and women’s can’t, the colonists were all women. The large diversity of the former could also cut down on the number of women required. But a bit of careful selection and reduction of key nutrients in her diet cut down the average woman’s mass by 15kg each. When you factor in the commensurate reduction in life support, their ship spent only 248 years in transit—fast enough to arrive by 2599-11-3, just under two months before the UFP’s deadline.